Advanced steroidal complex reviews

Abiraterone acetate (brand names Zytiga , Abiratas , Abretone , Abirapro ) is used in the treatment of prostate cancer . [2] [3] In addition to acting as an irreversible inhibitor of CYP17A1 (17α-hydroxylase/17,20-lyase), abiraterone inhibits 3β-hydroxysteroid dehydrogenase (3β-HSD), steroid 11β-hydroxylase (CYP11B1), 5α-reductase (via a metabolite ) [4] and certain hepatic cytochrome P450 enzymes (., CYP1A2 , CYP2C9 , and CYP3A4 ). [5] The drug acts as a partial antagonist of the androgen receptor and as an agonist of the estrogen receptor . [5] [6]

Advanced steroidal complex reviews

advanced steroidal complex reviews

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