Androgens are contraindicated in men with carcinomas of the breast or with known or suspected carcinomas of the prostate as well as in female who are or may become pregnant. When used to pregnant women, androgens cause virilization of the exterior genitalia of the female fetus. This virilization embrances clitoromegaly, unusual vaginal expansion, and combination of genital pleats to form a scrotal-like form. The grade of masculinization is linked to the amount of injection administrated also the age of the baby as well as is most expected to happen in the female fetus when the medicines are used in the first trimester. If the woman becomes pregnant during taking androgens; she have to be announce of the latent risk to the fetus.