Nonsteroidal antiinflammatory drugs and uncoupling of mitochondrial oxidative phosphorylation

FDA reviewed a meta-analysis of randomized clinical trials of cardiovascular and upper gastrointestinal events with non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs), conducted by the Coxib and traditional NSAID Trialists’ (CNT) Collaboration of the Clinical Trial Service and Epidemiological Studies Units at Oxford University. 2 We also reviewed observational studies and other scientific publications in the medical literature. 1 The findings of these studies were discussed at a joint meeting of the Arthritis Advisory Committee and Drug Safety and Risk Management Advisory Committee held on February 10-11, 2014 (for complete safety reviews, background information, and minutes of this meeting, click here ).

Nonsteroidal antiinflammatory drugs and uncoupling of mitochondrial oxidative phosphorylation

nonsteroidal antiinflammatory drugs and uncoupling of mitochondrial oxidative phosphorylation

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nonsteroidal antiinflammatory drugs and uncoupling of mitochondrial oxidative phosphorylationnonsteroidal antiinflammatory drugs and uncoupling of mitochondrial oxidative phosphorylationnonsteroidal antiinflammatory drugs and uncoupling of mitochondrial oxidative phosphorylationnonsteroidal antiinflammatory drugs and uncoupling of mitochondrial oxidative phosphorylationnonsteroidal antiinflammatory drugs and uncoupling of mitochondrial oxidative phosphorylation

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