Finally, there are instances when a progesterone-based hormone therapy might be used in the treatment of trans men. Progesterone may be used in some instances to help stop menstrual flow if testosterone therapy alone does not adequately stop the cycle after a reasonable period of treatment. A short course of progesterone may also be prescribed to induce a shedding of the uterine lining after testosterone therapy has progressed, in the event that there is any unusual buildup of the endometrium. This may help prevent spot bleeding as well as potentially decreasing the risk of uterine cancer. To learn more specifics about FTM testosterone therapy, please read the sections " FTM Testosterone Therapy Basics " and " FTM Testosterone Therapy and General Health ."
A cell type may divide and then form a small benign lump, known as a tumour, and the patient may then suffer from the effects of too much of the hormone the cell produces. If the tumour grows very large, even though still benign, it may squash the surrounding cells and stop them working (hypopituitarism), or push upwards and interfere with vision – a visual field defect. Very occasionally, the tumour may expand sideways and cause double vision as it affects the nerves that control eye movements. It should be emphasised that even when these tumours are large, they usually remain quite benign and very rarely spread to other parts of the body.
Some evidence suggests the circadian system regulates ghrelin, but this is uncertain. Ghrelin levels decrease after eating in proportion to caloric intake and rise between meals as hunger increases. Ghrelin is suppressed by daytime exercise but increased by evening exercise. Researchers speculate that circadian changes in other hormones may be the cause of the differences in ghrelin levels seen following exercise at different times of the day and However, no increase in hunger has been associated with the exercise-induced rise in ghrelin.